Doctor's Best, Stabilized R Lipoic Acid featuring BioEnhanced Na RALA, 100 mg, 60 veggie caps

Suitable for vegetarians

• Science-based nutrition
• Dietary supplement
• Defends against free radicals
• Recycles antioxidant nutrients such as vitamin C and vitamin E
• Helps maintain healthy blood sugar level when used as part of the diet

Alpha-lipoic acid (ALA, thioctic acid) is a naturally occurring vitamin-like nutrient that has been intensely investigated as a beneficial agent for a variety of bodily functions involving the nervous, cardiovascular, immune, and body cleansing systems. It exists as two enantiomers or stereoisomers: R-(+)-lipoic acid (RLA) and S-(-)-lipoic acid (SLA). It is produced in small amounts in the liver and other body tissues, where it is needed by enzymes to catalyze numerous essential chemical reactions in the body. For instance, ALA is essential inside the mitochondria of cells, where it is needed to metabolize glucose and direct calories into energy production.

ALA is considered to be a multimodal supplement because, aside from its enzymatic role in energy production, it acts by multiple mechanisms and displays diverse health-enhancing and antioxidant properties. Recently discovered is ALA's ability to regulate several genes linked to cell survival and oxidative stress. Therefore, in addition to its enzymatic role, ALA is a powerful antioxidant and performs a number of other vital functions related to its ability to modify the expression of various genes. Supplementing with ALA is, therefore, not so much a direct benefit to cells, but rather an indirect aid that effectively "kick starts" declining function, helping cells recover functionality that came more easily and naturally in youth.

Packaging

60 veggie caps

Ingredients

What is BioEnhanced Na-RLA Stabilized R-Lipoic Acid?

Alpha-lipoic acid comes in two forms, designated as "R-lipoic acid" and "S-lipoic acid." R- and S- lipoic acid are enantiomer isomers––molecules that appear as mirror images of each other. R-lipoic acid is naturally synthesized by humans, animals, and plants. S-lipoic acid is formed during chemical synthesis of alpha-lipoic acid, producing a "racemic" mixture of the two enantiomers that is often used in clinical studies on alpha-lipoic acid. Pharmacokinetic studies have shown that R-lipoic acid is more bioavailable than the S- form.1 For example, following single oral doses of 50 to 600 mg of racemic LA, maximum serum levels of the R- form were 40 to 50% higher than the S- lipoic form.2

Best Stabilized R-Lipoic Acid contains BioEnhanced Na-RLA, the sodium salt of R-Lipoic acid (RLA). Pure RLA is a very unstable molecule that has a tendency to polymerize with exposure to heat, light, and moisture. This presents problems for those wishing to supplement with RLA, since any of these conditions can lead to deactivation of the beneficial activity of alpha-lipoic acid. Unlike pure RLA, BioEnhanced Na-RLA is a stabilized form of RLA that won't degrade at high temperatures. By taking the sodium salt of RLA, its solubility is increased and it has an improved dissolution in the body. It is more bioavailable than regular RLA and has no solvent residues.3

Best Stabilized R-Lipoic Acid includes optically pure D-Biotin, the natural form of biotin. D-Biotin is a water-soluble vitamin and member of the vitamin B-complex that aids in the utilization of other B-complex vitamins. Integral to many of the activities of enzymes in the human body, D-biotin is necessary for the breakdown and conversion of fatty acids and carbohydrates into energy, allowing for the production of fats and excretion of protein breakdown products. Long-term administration of lipoic acid can lower the activities of the biotin-dependent enzymes pyruvate carboxylase and beta-methylcrotonyl-CoA carboxylase by competing with biotin.4 Supplementing with LA may thus increase the body's requirements for this vitamin.

About Doctor's Best

Founded in 1990 by supplement industry veteran Ken Halvorsrude and a wholistic physician, San Clemente-based Doctor's Best, Inc. manufactures and distributes dietary supplements throughout the US and overseas. Doctor's Best is known for high-quality products that are based on sound research in the field of nutritional science.

Safety

Do not use if pregnant or nursing. Keep out of reach of children. Please consult your health care provider if currently under care or treatment. Do not exceed recommended serving. See product packaging for additional safety information.

Disclaimer

Individual results may vary. This product is not intended to diagnose, treat, cure or prevent any disease. The statements on this website and all affiliates have not been evaluated by the FDA. Advice on treatment or care of an individual patient should be obtained through consultation with a trained health care practitioner.